Job Ref Number B02-10389
Salary: Offered at £45,103 per annum
Department Clinical and Movement Neurosciences
Location The Francis Crick Institute
Contract Type Fixed-term, funded by an MRC grant for one year or until 30 September 2027, with option to extend
Working Pattern Full time
About you
You will hold a PhD (or have submitted your thesis prior to starting) in Neuroscience, Molecular Biology, or a related discipline, with a strong foundation in biochemistry and molecular biology. You will be organised and able to manage your own workload effectively, prioritising tasks to meet deadlines with minimal supervision. You will have excellent written and verbal communication skills, with the ability to present complex scientific information clearly to a range of audiences and to work well within multidisciplinary teams and build effective working relationships. This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.
Job Description
We have established an international collaboration and assembled a large cohort to investigate the links between Type 2 diabetes, ageing, and neurodegenerative diseases. This is an exciting and novel project, supported by multidisciplinary expertise and based at the Francis Crick Institute, with opportunities to build collaborations within the international extracellular vesicle (EV) research community. We are seeking a Research Fellow to join our lab, based within the Neurodegeneration Biology Laboratory at the Francis Crick Institute, led by Professor Sonia Gandhi. Working across a range of human models, including patient-derived cells, biofluids, and brain tissue, you will further develop skills in molecular biology, cell imaging, and the analysis of complex datasets within a dynamic translational neuroscience research environment. You will work on the isolation and analysis of neuronal-derived extracellular vesicles from stored biosamples across several international studies to better understand disease mechanisms and identify biomarkers of disease progression. Established methods and protocols for EV isolation and characterisation will be used. In addition, EVs will be isolated from induced pluripotent stem cell (iPSC)-derived neuronal cultures from patients with Parkinson’s disease to investigate disease propagation in vitro.
Contact Name: Dr Dilan Athauda
Contact Email address: dilan.athauda@crick.ac.uk